| 摘要 |
<p>(A) Cmpds. Including alpha- & beta-anomers. R3, R5 & R6 = opt. subst. hydrocarbon residue, e.g. aliphatic, cycloaliphatic, cycloaliphatic-aliphatic, araliphatic or aromatic residues, all opt. subst. e.g. by (1-7C) alkyl, opt. substd. NH2, OH, Alkyl, SH, S alkyl, Hal, etc. With the proviso that R3 + R5 + R6 >= 4C atoms. (B) Acyl derivs. (II) of (I). (C) Salts of I & II. anti-inflammatories, anti-oedemics, & pharm. intermediates. Crude ethyl-3,4,6-tri-O-benzyl-D-glucofuranoside (500 g.) was stirred 16 h. vigorously at 70 deg. under N2, in 50% AcOH Aq. (500 ml), cooled to 30 deg., & evapd. in vac. at 35 deg. The residue in PhMe (1.2 l.) was washed with satd. NaHCO3-Aq., & H2O, dild. with hexane (4.2 l), filtered, dissolved in 50% EtOH-Aq. (2 vol.), & repptd., giving I, m.p. 68-71 deg.</p> |
