Derivs, antilipemic antichesterolemic - derivs, antilipemic anticholesteralemic

摘要

2-(p-Chlorophenoxy)-2-methyl-propionamide derivs. antilipemic anticholesteralemic. Title cpds. of formula (where R = -CnH2nOH, CmH2m-1(OH)2, CmH2mOZ, CmH2m-1(OZ)2; R1 = H, CnH2nOH, CmH2M OZ or when R1 = H, R opt. -C(CH2OH)3 or -C(CH2OZ)2 CH2OH or -N(R)R1 = a heterocyclic gp. such as piperidine or piperazine of 1 hydroxy lower alkyl gp. which is opt. esterified by Z, n = 1,3,4,5,6 m = 1-6, Z = 2 (p-chlorophenoxy)-2- methylpropionoyl) are prepd. by reaction of 2-(p-chlorophenoxy)-2-methyl-propionic acid or its active derivs. with an appropriate amine. Therapeutic medicine for use in animals and humans.