Cinnamyl amines, process for their preparation and pharmaceutical compositions containing them.

摘要

Compounds of formula I <CHEM> wherein X is an amino or hydroxy group; A and B being the same or different are hydrogen, alkyl, alkoxy, halogen or amino, or aminomethylene groups, when amino groups are alifatic or derived from nitrogen heterocycles; R is hydrogen, lower alkyl, a cyano or free or esterified carboxyl; Ra and Rb are alkyl groups, eventually substituted by Cl or OH, cycloalkyls, arylalkyls, heterarylalkyls, or if taken together with the nitrogen atom to which the are bound, they form a saturated or unsaturated heterocyclic ring. Compounds I, that are prepared by reacting acids II <CHEM> with amine III <CHEM> and formaldehyde have useful therapeutical properties.