IMMUNOSTIMULATING AGENT SUITABLE FOR ORAL ADMINISTRATION

摘要

PURPOSE:To obtain an immunostimulating agent suitable for oral administration by culturing a microbial strain belonging to the genus Aspergillus and capable of producing a mitogen-active substance in a medium containing a milk component, removing the microbial cells from the cultured product and using the obtained supernatant as an active component or fractionating the supernatant and using the obtained active fraction as an active component. CONSTITUTION:An immunostimulating agent composed mainly of a peptide obtained from a microbial strain belonging to the genus Aspergillus is mixed with a milk component to obtain an immunostimulating agent developing improved effect by oral administration. Preferably, a powdery immunostimulating agent is mixed with milk powder such as whole milk powder and skim milk. It has been difficult to develop the effect of an immunostimulating agent composed mainly of a peptide obtained from a microbial strain belonging to the genus Aspergillus by oral administration, however, the effect can be developed even by oral administration by the use of the subject immunostimulating agent.