摘要 |
<p><P>PROBLEM TO BE SOLVED: To enlarge the selection range of treatment by diversifying preventive agents or therapeutic agents of bone metabolism disorder (e.g. osteoporosis, arthritis, chronic arthrorheumatism, arthropathia, osteoarthropathy, Paget's disease, Bechterew's disease and hypercalcemia) by providing a highly safe new-type estrogen-substitutional drug (nonhormonal remedy) having physical restoration activities of the bone similar to the estrogen. <P>SOLUTION: The composition for preventing or treating the bone metabolism disorder contains a compound represented by formula (I) (wherein, each symbol is defined specifically) or a pharmaceutically acceptable salt thereof, or a compound represented by formula (X) (wherein, each symbol is defined specifically) or a pharmaceutically acceptable salt thereof. <P>COPYRIGHT: (C)2006,JPO&NCIPI</p> |