发明名称 Stabilization of lorazepam
摘要 This invention relates to orally disintegrable, lorazepam-containing dosage forms which are storage stable and disintegrable within about 90 seconds or less. In one embodiment, there is provided a storage stable, orally disintegrable dosage form comprising: protected lorazepam particles comprising lorazepam and polymeric material having a glass transition temperature of about 65° C. or above. Also disclosed is a method of producing a storage stable lorazepam containing tablet.
申请公布号 US2008031944(A1) 申请公布日期 2008.02.07
申请号 US20070888788 申请日期 2007.08.02
申请人 CIMA LABS INC. 发明人 BEREUTER LARRY;BROWN DAVID K.;MOE DEREK
分类号 A61K9/20;A61K9/14;A61K31/5513 主分类号 A61K9/20
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