发明名称 |
COAGULATION AND FIBRINOLYTIC CASCADES MODULATOR |
摘要 |
The invention provides a thromboplastin reagent comprising: tissue factor, a phospholipid and a polyphosphate that acts as a blocker of tissue factor pathway inhibitor (TFPI). Also provided are a composition for promoting clotting comprising polyphosphate, and a reagent for a clotting assay also comprising polyphosphate together with an activator of clotting. Methods for stopping or slowing wound bleeding and fibrinolysis using compositions comprising polyphosphate are also disclosed. |
申请公布号 |
CA2600907(C) |
申请公布日期 |
2016.06.28 |
申请号 |
CA20062600907 |
申请日期 |
2006.02.23 |
申请人 |
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS |
发明人 |
MORRISSEY, JAMES H.;SMITH, STEPHANIE A.;DOCAMPO, ROBERTO;MUTCH, NICOLA J. |
分类号 |
C07K14/745;C12Q1/56 |
主分类号 |
C07K14/745 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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