| 摘要 |
FIELD: medicine.SUBSTANCE: invention describes a method for administering a pharmaceutically active compound to patient. Method includes obtaining a powdered composition, mixing composition with a liquid or semi-solid product to obtain a stable solution or dispersion and oral administration of solution or dispersion to a patient. Powdered composition contains from 1 to 30 wt% of pharmaceutically active compounds and from 70 to 99 wt% of protein, where protein is a bovine serum albumin or human serum albumin. Pharmaceutically active compound is characterised as lipophilic or hydrophobic, capable of binding with protein plasma and orally biologically available. Albumin is not covalently bound with pharmaceutically active compound. Present invention also provides liquid or semi-solid preparations of composition; method of producing compositions and pharmaceutical kit containing composition.EFFECT: compositions are characterised by intensification of absorption and bioavailability of drug.38 cl, 4 dwg, 4 tbl, 5 ex |
