发明名称 |
DERIVATER AF FLUOREN, ANTHRACEN, XANTHEN, DIBENZOSUBERON OG ACRIDIN OG ANVENDELSER DERAF |
摘要 |
Chemical agents, such as disulfonamide derivatives of fluorene, anthracene, xanthene, dibenzosuberone and acridine, and similar heterocyclic ring structures, including salts thereof, that act as anti-cancer and anti-tumor agents, especially where such agents modulate the activity of the Wnt/&bgr;-catenin signaling pathway, and serve to reduce &bgr;-catenin levels present in cells, such as cancer cells, or where the agents modulate levels of gene expression in cellular systems, including cancer cells, are disclosed, along with methods for preparing such agents, as well as pharmaceutical compositions containing such agents as active ingredients and methods of using these as therapeutic agents. |
申请公布号 |
DK2152258(T3) |
申请公布日期 |
2016.08.22 |
申请号 |
DK20080754344T |
申请日期 |
2008.05.09 |
申请人 |
Dogwood Pharmaceuticals, Inc. |
发明人 |
CHOLODY, Wieslaw, M.;ZANG, Yi;ZUCK, Karina;WATTHEY, Jeffrey, W.H.;OHLER, Zoe;STROVEL, Jeffrey;OHLER, Gene;PADIA, Janak;CHELLAPPAN, Sheela |
分类号 |
A61K31/185;A61K31/135 |
主分类号 |
A61K31/185 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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