| 摘要 |
A material for use as a bone implant or bone substitute for use in replacing or repairing bone is described, together with a method for forming the material. The material comprises: (a) a titanium or titanium alloy substrate comprising a first surface having a first surface area; (b) a plurality of metallic beads adhered to the first surface, wherein the plurality of metallic beads are micron scale structures that collectively form a second surface having a second surface area that is greater than the first surface area, and (c) a surface layer on the plurality of metallic beads comprising alkali titanates, wherein the surface layer has a thickness between 100 and 300 nanometers, and wherein the surface layer comprises a plurality of nanoscale structures that collectively form a third surface comprising a third surface area that is greater than the second surface area. |
