摘要 |
<p>Amines (I) and their acid salts- R1 = H, alkyl R2 = H, OH R3,4 = OH, opt. etherified, halogen, alkyl A = Th.CH2CHR5.CH2 or Th.CH2CH2, where Th = theobromine or theophylline and R5 = H or OH Z = A, H or alkyl; when H or alkyl, A = Th.CH2CHOH-CH2. nor-ephedrino-N-hydroxypropyltheophylline (II), nor-ephedrino-N-di-(hydroxypropyltheophylline), (beta-(beta'-phenyl-beta'-hydroxyethylamino)-hydroxypropyl) -theophylline, ephedrino-N-hydroxypropyltheophylline. The cpds. show marked sympathicomimetic action. Also cardiac and circulatory activity.</p> |