| 摘要 |
The invention provides N-phenyl, N-alkanoylpiperidines which have an alkylene or hydroxy or keto alkylene radical attached to the nitrogen of the piperidine ring said alkylene group having a cyclic substituent selected from 1,2,3,4-tetrahydro-naphthyl, indenyl, idolyl, benzo(b)-thienyl, pyrimidinyl, quinolyl, benzo-1,4-dioxanyl and benzindolyl with the proviso that when a hydroxy or keto alkylene radical is present the cyclic substituent may also be selected cycloalkyl containing from five to seven carbon atoms or a phenyl radical and said cyclic substituents may be substituted. The compounds exhibit one or more of the following pharmacological activities, analgesic activity, anti-oxotremorine activity, hypotensive activity, anti-inflammatory activity, CNS activity or blood platelet aggregation or are intermediates for such compounds.
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