| 摘要 |
The invention relates to compounds of the formula <IMAGE> I wherein R1 is hydrogen or methyl; <IMAGE> wherein R2 is lower alkyl; R3 is phenyl, or phenyl substituted by 1 to 3 substituents selected from the group consisting of halo, lower alkyl, and lower alkoxy; and R4 is hydrogen or methyl or the corresponding hydroxy acid of formula <IMAGE> II <IMAGE> and R1, R2, R3 and R4 are as described above; or a pharmaceutically acceptable salt of said acid, a C1-4 alkyl ester of said acid, an acetylamino-substituted-C1-4 alkyl ester of said acid, a phenyl-dimethylamino ester of said acid or a alpha -monoglyceride of said acid. The compounds of formulas I and II are useful as agents for the treatment of hyperproliferative skin diseases such as psoriasis.
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