ELEKTROKATALYTISCHE ASYMMETRISCHE DIHYDROXYLIERUNG VON OLEFINEN
摘要
<p>A process is disclosed in which optically active glycols are produced through an electrolytic asymmetric dihydroxylation (ADH) reaction involving olefins as substrates. The ADH reaction is mediated by a catalytically active amount of osmium tetroxide or osmium-containing precursor in a protic medium in the presence of chiral ligand. Any lower valent osmium species produced in the course of the ADH reaction is regenerated electrolytically either directly in the absence of a secondary oxidant or indirectly in the presence of a secondary oxidant that itself undergoes electrolytic regeneration.</p>
申请公布号
DE69319342(D1)
申请公布日期
1998.07.30
申请号
DE1993619342
申请日期
1993.02.19
申请人
SEPRACOR, INC., MARLBOROUGH, MASS., US
发明人
GAO, YUN, FRAMINGHAM, MA 01701, US;ZEPP, CHARLES M., BERLIN, MA 01503, US