发明名称 SUBSTITUTED 2,4-IMIDAZOLIDINEDIONES
摘要 Substituted 2,4-imidazolidinediones A b s t r a c t Are prepared either by reaction of .alpha.-aminocarboxylic acid derivatives with appropriately substituted biphenylmethyl halides and subsequent cyclization with isocyanates or by reaction of N-benzyl-substituted a-aminocarboxylic acid derivatives with tetrazolylphenylboronic acids or by reaction of sulphonyl-substituted benzyl halides with aaminocarboxylic acid derivatives and subsequent cyclization with isocyanates. The compounds according to the invention can be employed as active compounds in medicaments, preferably for the treatment of arterial hypertension and arteriosclerosis.
申请公布号 CA2124057(A1) 申请公布日期 1994.11.26
申请号 CA19942124057 申请日期 1994.05.20
申请人 BAYER AKTIENGESELLSCHAFT 发明人 KRAMER, THOMAS;HANKO, RUDOLF;DRESSEL, JUERGEN;FEY, PETER;HUEBSCH, WALTER;MUELLER, ULRICH;MUELLER-GLIEMANN, MATTHIAS;BEUCK, MARTIN;BISCHOFF, HILMAR;WOHLFEIL, STEFAN;DENZER, DIRK;KAZDA, STANISLAV;STASCH, JOHANNES-PETER;KNORR, ANDREAS;ZAISS, SIEGFRIED
分类号 A61K31/415;A61P9/10;A61P9/12;C07D207/48;C07D257/04;C07D403/10;C07D403/12;(IPC1-7):C07D403/02;C07F5/02;C07D401/12;C07D413/12;C07D295/26;A61K31/445;A61K31/495;A61K31/535 主分类号 A61K31/415
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