发明名称 Treatment of schizophrenia with ampakines and neuroleptics
摘要 This invention relates to treatment of schizophrenia and related psychotic disorders, including enhancement of receptor functioning in synapses in brain networks responsible for higher order behaviors. In a particular aspect, the invention relates to methods for the use of AMPA receptor up-modulators in conjunction with antipsychotics for the treatment of schizophrenia. Kits containing the compositions in appropriate form for administration are also provided.
申请公布号 US6166008(A) 申请公布日期 2000.12.26
申请号 US19980179341 申请日期 1998.10.26
申请人 CORTEX PHARMACEUTICALS, INC.;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 发明人 JOHNSON, STEVEN A.;LYNCH, GARY S.;ROGERS, GARY A.
分类号 C07D295/18;A61K31/357;A61K31/36;A61K31/38;A61K31/4025;A61K31/443;A61K31/445;A61K31/4453;A61K31/4525;A61K31/453;A61K31/454;A61K31/4545;A61K31/496;A61K31/498;A61K31/519;A61K31/535;A61K31/5355;A61K31/5365;A61K31/5375;A61K31/5377;A61K31/541;A61K31/5415;A61K31/55;A61K31/5513;A61K31/554;A61K45/00;A61K45/06;A61P25/18;C07D211/70;C07D235/08;C07D241/42;C07D263/56;C07D271/12;C07D285/26;C07D317/46;C07D317/54;C07D317/60;C07D405/06;C07D405/12;C07D413/06;C07D498/04;C07D498/14;(IPC1-7):A61K31/535 主分类号 C07D295/18
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