METHODS FOR ISOLATING CENTROMERE DNA

摘要

The invention provides efficient methods for the isolation of centromeres from potentially any organism. The methods represents an advance over the prior art in that costly and labor intensive mapping programs are not required. Using the technique, methylated centromere DNA may be isolated from potentially any centromere in an organism. The technique is amenable to mass screenings employing use of arrays comprising libraries of DNA from a target species.