CONTROLLED RELEASE GRANULES COMPRISING POROUS SILICA CORE

摘要

The present invention relates to controlled release granules for medical us e comprising a drug loaded porous silica particle, and at least one layer of a controlled release coating material, characterized in that the drug loaded porous silic a core is prepared by immersing dry porous silica particles with a solution, suspensio n or emulsion comprising at least one pharmacologically active drug and the resulting wet drug loaded porous silica core is subsequently dried again. Furthermore, the invention concerns a method for preparing the controlled release composition .