| 发明名称 |
6-membered heterocyclic compounds useful for selective inhibition of the coagulation cascade |
| 摘要 |
The present invention relates to compounds, and prodrugs thereof, compositions and methods useful for preventing and treating thrombotic conditions in mammals. The compounds of the present invention, and prodrugs thereof, selectively inhibit certain proteases of the coagulation cascade.
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| 申请公布号 |
US6969715(B2) |
申请公布日期 |
2005.11.29 |
| 申请号 |
US20020263637 |
申请日期 |
2002.10.03 |
| 申请人 |
PHARMACIA CORPORATION |
发明人 |
SOUTH MICHAEL S.;WEBBER RONALD K.;HUANG HORNG-CHIH;TOTH MIHALY V.;MOORMANN ALAN E.;SNYDER JEFFERY S.;SCHOLTEN JEFFREY A.;GARLAND DANNY J.;RUEPPEL MELVIN L.;NEUMANN WILLIAM L.;LONG SCOTT;HUANG WEI;TRUJILLO JOHN;PARLOW JOHN J.;JONES DARIN E.;CASE BRENDA;HAYES MICHAEL J. |
| 分类号 |
C07D249/12;A61K31/451;A61K31/495;A61K31/50;A61K31/513;A61K31/53;A61K31/535;A61K45/00;A61P7/02;A61P9/10;A61P43/00;C07C257/18;C07D207/32;C07D211/56;C07D211/98;C07D213/74;C07D231/38;C07D231/48;C07D237/04;C07D239/10;C07D239/22;C07D241/04;C07D241/20;C07D249/14;C07D253/06;C07D253/075;C07D263/48;C07D265/02;C07D277/42;C07D307/22;C07D333/36;C07D401/12;C07D403/10;C07D413/12;C07D471/04;(IPC1-7):C07D253/06 |
主分类号 |
C07D249/12 |
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