摘要 |
<p>The invention is related to the process of fermentation with production strain Bacillus polymyxa for industrial production of antibiotic polymyxin B with yield from 1.8 to 2.8 g/l of filtrate of fermentation broth at temperature 28° C., pressure 40−70 kPa, aeration from 0.4 to 1 vvm, concentration of dissolved oxygen minimal 60%, maintenance of pH and optimal concentration of glucose and ammonium ions.</p> |