发明名称 |
Forms of soluble pyrroloquinoline quinone-dependent glucose dehydrogenase |
摘要 |
The present invention relates to improved variants of soluble pyrroloquinoline quinone (PQQ)-dependent glucose dehydrogenases (s-GDH), to genes encoding mutated s-GDH, to mutant proteins of s-GDH with improved substrate specificity for glucose, and to different applications of these s-GDH variants, particularly for determining concentrations of sugar, especially of glucose in a sample.
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申请公布号 |
US7547535(B2) |
申请公布日期 |
2009.06.16 |
申请号 |
US20050298778 |
申请日期 |
2005.12.09 |
申请人 |
ROCHE DIAGNOSTICS OPERATIONS, INC. |
发明人 |
KRATZSCH PETER;SCHMUCK RAINER;BECK DANIELA;SHAO ZHIXIN;THYM DETLEF;KNAPPE WOLFGANG-REINHOLD |
分类号 |
C12N9/04;G01N33/66;C07H21/04;C12M1/40;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N11/02;C12N15/09;C12N15/53;C12P21/02;C12Q1/32;C12Q1/54 |
主分类号 |
C12N9/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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