The present invention is directed to pyrimidine compounds which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 10 (PDE10). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction.
申请公布号
DK2748151(T3)
申请公布日期
2016.07.04
申请号
DK20120826375T
申请日期
2012.08.20
申请人
Merck Sharp & Dohme Corp.
发明人
COX, Christopher, D.;DUDKIN, Vadim;KERN, Jeffrey;LAYTON, Mark, E.;RAHEEM, Izzat, T.