发明名称 |
NICOTINE-DIKETOPIPERAZINE MICROPARTICLE FORMULATIONS AND METHODS OF MAKING THE SAME |
摘要 |
This invention relates to nicotine microparticles formulations made with the help of a diketopiperazine compound, in particular fumaryl diketopiperazine (FDKP). The invention relates to the various types of microparticles that can be made, in particular nicotine-coated and nicotine-loaded microparticles. The invention further relates to the various methods that can be used in making the microparticles. One particular method involves making FDKP microparticles which are further surface- coated with nicotine. Another particular method involves mixing nicotine with FDKP2" and/or FDKP and then forming microparticles which contain nicotine throughout their volume. The invention also relates to the use of this microparticles in tobacco related therapies, such as tobacco replacement or tobacco withdrawal. |
申请公布号 |
WO2016118328(A1) |
申请公布日期 |
2016.07.28 |
申请号 |
WO2016US12437 |
申请日期 |
2016.01.07 |
申请人 |
SANSA CORPORATION (BARBADOS) INC.;STENZLER, ALEX |
发明人 |
ZAMEL, NOE;SLUTSKY, ARTHUR;ELLIS, STEVEN |
分类号 |
A61K31/465 |
主分类号 |
A61K31/465 |
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