发明名称 イミダゾピリジン化合物
摘要 [Problem] An excellent drug for treating or preventing cardiovascular diseases, based on cGMP production enhancing action due to soluble guanylate cyclase activating action, is provided. [Means for Solution] It was found that imidazopyridine compounds having a carbamoyl group at the 3-position and a substituent bonded at the 8-position via an oxygen atom in an imidazo[1,2-a]pyridine skeleton exhibits a cGMP production enhancing action by a potent soluble guanylate cyclase activating action, and is useful as a drug for treating or preventing various soluble guanylate cyclase-related cardiovascular diseases, thereby completing the present invention.
申请公布号 JP5975025(B2) 申请公布日期 2016.08.23
申请号 JP20130518087 申请日期 2012.05.29
申请人 アステラス製薬株式会社 发明人 古賀 祐司;前野 恭一;佐藤 一平;今村 佳正;花澤 毅;飯田 真依子;大根 和彦;今村 健一郎;渡辺 翼;野澤 栄典;柴田 洋
分类号 C07D471/04;A61K31/437;A61K31/439;A61K31/444;A61K31/4545;A61K31/497;A61K31/501;A61K31/506;A61K31/53;A61K31/5377;A61K31/541;A61P9/00;A61P9/10;A61P9/12;A61P29/00;A61P43/00 主分类号 C07D471/04
代理机构 代理人
主权项
地址