摘要 |
<p>Cpds. of formula (I) (where both thienyl gps. can be substd. by one or more lower alkyl gps; A-B is C(OH)-CHR7 or C=CR7; R1, R2 R6 and R7 are H or lower alkyl, R3 is H or OH; R4 and R5 are H, halogen, OH, lower alkyl, lower haloalkyl, or lower alkoxy, and one or both thienyl gps. can also be linked with A-B in the 2-posn. when R6 and/or R7 is alkyl) and their optical isomers and diastereoisomers and salts are coronary vasodilators, increasing peripheral and cerebral circulation.</p> |