| 摘要 |
<p>Novel compounds, suitable for use as intermediates for the preparation of antibiotically active cephalosporins, of the formula I <IMAGE> wherein Z denotes <2bL>S or <2bL>S->O in the alpha - or ss-configuration; R<1> denotes a free or protected amino group; R<4> denotes hydrogen or a carboxyl protective group; R<5> denotes a hydrogen atom, an acyl group or a protected carboxyl group; and R<8> denotes hydrogen or a 7 alpha -lower alkyl or 7 alpha -lower alkoxy group, are prepared by elimination of hydrogen halide from corresponding compounds which carry a halogenomethyl group, other than the fluoromethyl group, as a substituent in the 2-position.</p> |
