| 摘要 |
The present invention relates to an anti-caries oral composition which comprises a fluorine-containing anticaries agent and a particulate hydroxyapatite abrasive material. The compatibility of the hydroxyapatite with the fluorine compound is improved by pretreating the surface of the hydroxyapatite material with compounds that block the hydroxygroups, present at the surface of the hydroxyapatite. Such compounds are preferably alkaline materials such as sodium hydroxide, sodiumtrimetaphosphate, tetrasodiumpyrophosphate, sodium carbonate.
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