| 摘要 |
<p>A composition for the rectal administration of difficultly absorbable peptides, comprising a difficultly absorbable peptide as the active ingredient, a C8 to C14 saturated fatty acid or an avirulent salt thereof, and a protease inhibitor. The composition allows peptides which have been believed to be difficult to absorb to be absorbed efficiently through the rectal mucosa, so that it can achieve an excellent pharmacological efficacy without resort to injection which is painful and is limited in its administration. Further it has an economic advantage because it can provide a pharmaceutical preparation of relatively expensive peptides witha reduced loss thereof.</p> |
