发明名称 |
COMPOSITIONS AND METHODS TO INHIBIT THE ACTIVATION OF ACTIVE FACTOR XIII |
摘要 |
Compositions and methods for inhibiting the activation and/or active state of a precursor protein are provided. Compositions provided can bind to a cleavage site of a precursor protein. Also provided are compounds useful for generating inhibitor compositions. Application of the invention to the treatment of myocardial infarction and other thrombotic conditions is specifically provided. Further provided are antibodies specific for active Factor XIII. |
申请公布号 |
WO9215609(A1) |
申请公布日期 |
1992.09.17 |
申请号 |
WO1992US01926 |
申请日期 |
1992.03.11 |
申请人 |
THE GENERAL HOSPITAL CORPORATION;BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
REED, GUY, L.;MATSUEDA, GARY, R.;HABER, EDGAR |
分类号 |
A61K38/55;A61K38/00;A61K39/00;A61P7/02;C07K7/06;C07K14/745;C07K14/755;C07K16/00;C07K16/40;C12N9/10 |
主分类号 |
A61K38/55 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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