摘要 |
<p>A process for easily preparing retinol useful in the fields of drugs, feed additives and food additives, by reacting a halogenated sulfone derivative represented by general formula (1): wherein Ar is optionally substituted aryl; and X is halogeno) with a base. Such intermediates can be easily prepared by reacting a diol compound represented by general formula (2): wherein Ar is as defined above), which can be derived from a relatively inexpensive raw material, with a Group 4 transition metal halide without protecting the primary hydroxyl group.</p> |