发明名称 PROCESS FOR THE PREPARATION OF RETINOL AND INTERMEDIATES THEREFOR
摘要 <p>A process for easily preparing retinol useful in the fields of drugs, feed additives and food additives, by reacting a halogenated sulfone derivative represented by general formula (1): wherein Ar is optionally substituted aryl; and X is halogeno) with a base. Such intermediates can be easily prepared by reacting a diol compound represented by general formula (2): wherein Ar is as defined above), which can be derived from a relatively inexpensive raw material, with a Group 4 transition metal halide without protecting the primary hydroxyl group.</p>
申请公布号 WO2000024713(P1) 申请公布日期 2000.05.04
申请号 JP1999005748 申请日期 1999.10.19
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