| 发明名称 |
METHODS OF TREATING CANCER WITH HIGH POTENCY LIPID-BASED PLATINUM COMPOUND FORMULATIONS ADMINISTERED INTRAPERITONEALLY |
| 摘要 |
One aspect of the invention relates to methods of treating cancer in a patient comprising administering intraperitoneally to a patient in need thereof a cancer treating effective amount of a composition comprising a lipid-complexed platinum compound wherein the concentration of the platinum compound of the lipid-complexed platinum compound composition is greater than about 1.2 mg/ml. Another aspect of the invention relates to lipid-complexed platinum compound compositions where the concentration of the platinum compound is greater than about 1.2 mg/ml. |
| 申请公布号 |
US2016166608(A1) |
申请公布日期 |
2016.06.16 |
| 申请号 |
US201514796920 |
申请日期 |
2015.07.10 |
| 申请人 |
Insmed Incorporated |
发明人 |
Pilkiewicz Frank G.;PEREZ-SOLER Roman;ZOU Yiyu;PERKINS Walter R.;LEE Jin K.;MALININ Vladimir |
| 分类号 |
A61K33/24;A61K9/127;A61K47/48;A61K9/16 |
主分类号 |
A61K33/24 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of treating cancer in a patient comprising administering intraperitoneally to a patient in need thereof a cancer treating effective amount of a composition comprising a lipid-complexed active platinum compound, wherein the lipid complexed active platinum compound has a lipid to drug (L/D) ratio of less than about 1 by weight. |
| 地址 |
Bridgewater NJ US |
