| 摘要 |
New Extractive Technique For the Recovery of Macrocyclic Antibiotics, Especially Rapamycin, From Broth Fermentation Solutions This invention relates to a process of recovering a macrolide antibiotic, especially a tricyclic macrolide such as rapamycin from concentrates of fermentation broth extracts or mother liquors whereby acidic and/or basic components formed in the fermentation process are removed by utilizing aqueous base or acid extraction procedures from a water-immiscible solution of said concentrate and non-polar components are separated from the macrolide by selective solubility.
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