| 摘要 |
A method of preparing an injectable pharmaceutical or veterinary composition which comprises either diclofenac or a salt thereof and 2-hydroxypropyl betacyclodextrin, or an inclusion complex of diclofenac or a salt thereof and 2hydroxypropyl beta-cyclodextrin, includes the step of dissolving either the diclofenac or salt thereof and the 2-hydroxypropyl beta-cyclodextrin, or the inclusion complex, in water to form a solution, the water having been acidified to a pH such that the pH of the solution is from 6,0 to 8,5 inclusive, in the absence of a phosphate buffer. The composition so produced has good stability on storage.
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