摘要 |
A pharmaceutical compound of the formula <IMG> in which m is 0, 1 or 2, n and q are each 0 or 1 to 5, and p is 0 or 1, X is -CO2H or tetrazolyl, Y is -CH=CH-, and Z is (i) phenyl, naphthyl or thienyl, said phenyl, naphthyl and thienyl being optionally substituted, (ii) -CHR1R2 where R1 and R2 are each phenyl, naphthyl or thienyl, said phenyl, naphthyl and thienyl being optionally substituted, (iii) =CR1R2 where R1 and R2 are each phenyl, naphthyl or thienyl, said phenyl, naphthyl and thienyl being optionally substituted, or (iv) <IMG> where r is 0 or 1 to 3 and the phenyl rings are optionally substituted; provided that when Z is phenyl and m is 1, p is 1; and salts and esters thereof.
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申请人 |
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发明人 |
CARRERA, JESUS EZQUERRA;ESTEBAN, ALMUDENA RUBIO;MANN, ANDRE;SCHOENFELDER, ANGELE;SCHOEPP, DARRYLE DARWIN;TERCERO, CONCEPCION PEDREGAL;WERMUTH, CAMILLE-GEORGES |