1,3-diazoheterocycles from gamma-cyano-varboxylic acid - halides and hydrohalides

摘要

Halogen substd. 1,3-diazoheterocycles are prepd. from gamma-cyanocarboxylic acid halides and hydrohalides. Starting materials may be beta-cyanoisocyanates, beta-cyanoisothiocyanates or beta-aminonitriles and pref. beta-aminonitrile is reacted with reagents e.g. phosgene or thiophosgene and the mixture used as starting material without isolating intermediates.