摘要 |
Cephalosporin compounds represented by the formula <IMAGE> wherein R is an acylamino group <IMAGE> and R' is for example phenyl or furyl, R'' is H or CH3; or R is a substituted ureido group <IMAGE> and R'' is H or CH3, R''' is e.g., C1-C3 alkyl; or R is a cyclic ureido group, e.g., imidazolidine-2-one-1-yl and wherein R1 is phenyl, substituted phenyl, thienyl, or furyl; are broad spectrum antibiotics exhibiting an expanded spectrum of activity vs. gram-negative microorganisms. |