| 发明名称 |
Method for the production of antibodies. |
| 摘要 |
<p>The invention relates to a novel method for the generation of monoclonal antibodies. The method involves the combination of a clonal expansion of B-lymphocytes followed by or preceded by a selection of B-lymphocytes which produce antibodies with the desired specificity. The selected lymphocytes are immortalized. The invention makes it possible to use any source of B-lymphocytes no matter how small.</p> |
| 申请公布号 |
EP0488470(A1) |
申请公布日期 |
1992.06.03 |
| 申请号 |
EP19910203080 |
申请日期 |
1991.11.25 |
| 申请人 |
AKZO N.V. |
发明人 |
STEENBAKKERS, PETRUS GERARDUS ANTONIUS |
| 分类号 |
C07K16/00;C12N5/10;C07K16/08;C07K16/10;C07K16/28;C12N5/16;C12N15/02;C12P21/08;C12N15/09;C12R1/91 |
主分类号 |
C07K16/00 |
| 代理机构 |
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代理人 |
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