摘要 |
PCT No. PCT/SE87/00480 Sec. 371 Date Jun. 1, 1987 Sec. 102(e) Date Jun. 1, 1987 PCT Filed Oct. 16, 1986 PCT Pub. No. WO87/02250 PCT Pub. Date Apr. 23, 1987.A process is provided for preparing an immunogenic complex containing antigenic proteins and peptides with hydrophobic domains, whereby proteins or peptides from viruses, mycoplasmas, bacteria, parasites, animal cells with hydrophobic domains are mixed with one or more solubilizing agents, whereby complexes are formed between proteins or peptides and the solubilizing agent, where after the proteins or peptides are separated from solubilizing agent in the presence of, or are separated from, the solubilizing agent and directly transferred to a glycoside solution, containing one or more glycosides with hydrophobic and hydrophilic domains in a concentration of at least the critical micellar concentration, thereby forming a protein complex which is isolated and purified, characterized in that lipids are added before the complex is isolated and purified.
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