发明名称 ALKENYLCARBOXYLIC ACIDS GUANIDIDES SUBSTITUTED BY FLUOROPHENYL GROUPS, THEIR PREPARATION METHOD, THEIR USE AS DRUG OR DIAGNOSTIC AGENT, AND MEDICAMENTS CONTAINING THEM
摘要 Disclosed are compounds of the general formula (I) wherein R1, R2, R3, R4 and R5 denote independently from each other H, F provided at least one is F; R6, R7 is H, 1 - 8C alkyl, 3 - 8C cycloalkyl, or phenyl (optionally substituted); and their pharmaceutically acceptable salts. Said compounds are effective as Na+/H+ exchange inhibitors; process for their preparation, their use as medicinal or diagnostic agent as well as a medicament containing them.
申请公布号 SK65196(A3) 申请公布日期 1996.12.04
申请号 SK19960000651 申请日期 1996.05.17
申请人 HOECHST AG 发明人 SCHWARK JAN-ROBERT;LANG HANS-JOCHEN;KLEEMANN HEINZ-WERNER;WEICHERT ANDREAS;SCHOLZ WOLFGANG;ALBUS UDO
分类号 A61K31/165;A61K31/155;A61K31/16;A61P1/16;A61P3/08;A61P9/06;A61P9/08;A61P9/10;A61P13/02;A61P15/00;A61P35/00;A61P43/00;C07C277/08;C07C279/22;(IPC1-7):C07C279/10 主分类号 A61K31/165
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