Agents and methods for modulation of zinc transfer by metallothionein

摘要

A method is provided for the treatment of diseases of plants and animals where such diseases involve disturbance of zinc homeostasis. The method involves administration of therapeutic agents that after cellular oxidation potential so as to oxidize metallothionein and thereby release zinc ions, or as to maintain metallothionein in a reduced state so as to prevent transfer of zinc from metallothionein to zinc acceptors.