Dialysis unit for purifying blood, particularly in patients affected with organ failure

摘要

A colloidal solution derived, for example, from the bloodstream of a patient affected with acute and/or chronic organ failure, and in the form of ultrafiltrate, plasmafiltrate or whole blood, is purified of toxins, in particular PAF, bilirubin, endotoxins, free radicals and protein-bound toxins, such as indoxyl-sulfate, by dialysis through an appropriate semipermeable membrane, the opposite sides of which are contacted respectively by the solution to be purified and by a wash solution containing a predetermined concentration of liposomes generally larger than the pores of the semipermeable membrane; the dialysis unit presents a pack of highly permeable, hollow fibers connected internally to a first circuit containing the solution to be purified, and which are immersed in a counterstream of the wash solution containing liposomes; the wash solution circulates in a second circuit presenting means for feeding the liposomes into the wash solution, and possibly a perfusion cartridge in series with the second circuit and in which the wash solution containing the liposomes percolates through a filter of activated-carbon or synthetic resin particles covered with continuous phospholipid membranes.