PRODUCTION OF 4-NITRODIPHENYLAMINE AND 4-NITROANILINE FROM PHENYLUREA

摘要

PURPOSE: A process for preparing the title compound by reaction of phenylurea capable of easily manufacturing from urea and aniline with nitrobenzene using an alkali metal base such as sodium hydroxide or an alkali earth metal base is provided, which can prevent generation of ortho compounds such as 2-NDPA and phenazine and azoxybenzene as byproducts by passing oxygen and air through a reaction atmosphere. The process can also generate no harmful material such as chlorine and reduce an amount of waste. CONSTITUTION: In a process for manufacturing 4-nitrodiphenylamine and 4-nitroaniline using an aromatic hydrogen nucleophilic reaction, phenylurea and nitrobenzene are reacted at 20 to 150deg.C in the presence of a base and a polar organic solvent. The base is used in an amount of 1 to 10 times by molar ratio based on the phenylurea and selected from sodium hydroxide, sodium hydride, potassium hydride, potassium hydroxide, t-butoxy potassium and sodium amide.