| 发明名称 |
CALCIUM CHANNEL PROTEINS AND USES THEREOF |
| 摘要 |
Described herein are compositions and uses thereof related to Ca2+ release-activated Ca2+ (CRAC) channel activity. Also described herein CRAC channel modulators for treating diseases or conditions that would benefit from inhibition of SOC channel activity. |
| 申请公布号 |
US2016169868(A9) |
申请公布日期 |
2016.06.16 |
| 申请号 |
US201313733095 |
申请日期 |
2013.01.02 |
| 申请人 |
CalciMedica, Inc. |
发明人 |
Stauderman Kenneth A.;Roos Jack;Velicelebi Gonul |
| 分类号 |
G01N33/50 |
主分类号 |
G01N33/50 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of identifying an agent that modulates intracellular calcium comprising: contacting one or more test cells comprising a stromal interacting molecule (STIM) protein or a portion thereof and an Orai protein or a portion thereof, assessing the effect(s) of the agent on intracellular calcium, and identifying an agent that has an effect on intracellular calcium. |
| 地址 |
La Jolla CA US |
