摘要 |
The invention relates to new and original sigma ligants : (mono- or di-alkylaminoalkyl) -y-butyrolactons their analogs tetrahydrofurans, the (1-adamantyl) benzene(s) alkylamines the N,N Dialkyll a- [(adamntyl-1) Benzyloxy-2] alkylamines and the 3-cyclopentyl adamantyl - amines or alkylamines or alkylphenylamines,their enantiomers or diastereoisomers and their pharmaceutically acceptables, racemic salts with pro-apoptic and/or anti-apoptotic action on the cells biochemical process and with anti-cancer, anti-metastatic, anti-chronic inflammatory, neuroprotective , anti-depressive, anti-convulsive, nooanaleptic or sedative activity. |