发明名称 NEW SIGMA LIGANDS with anti-apoptotic and/or pro-apoptotic action on the cells biochemical mechanisms and neuroprotective, anti-cancer, anti-metastatic, and anti-chronic inflammatory properties.
摘要 The invention relates to new and original sigma ligants : (mono- or di-alkylaminoalkyl) -y-butyrolactons their analogs tetrahydrofurans, the (1-adamantyl) benzene(s) alkylamines the N,N Dialkyll a- [(adamntyl-1) Benzyloxy-2] alkylamines and the 3-cyclopentyl adamantyl - amines or alkylamines or alkylphenylamines,their enantiomers or diastereoisomers and their pharmaceutically acceptables, racemic salts with pro-apoptic and/or anti-apoptotic action on the cells biochemical process and with anti-cancer, anti-metastatic, anti-chronic inflammatory, neuroprotective , anti-depressive, anti-convulsive, nooanaleptic or sedative activity.
申请公布号 GR1005865(B) 申请公布日期 2008.04.07
申请号 GR20070100020 申请日期 2007.01.17
申请人 ANAVEX LIFE SCIENCES CORP. 发明人 VAMVAKIDIS ALEXANDROS
分类号 A61K31/341;A61K31/343;A61P25/00 主分类号 A61K31/341
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