发明名称 ANTI-EPRS MONOCLONAL ANTIBODY AND USES THEREOF
摘要 The present invention relates to an anti-EPRS antibody which specifically binds to EPRS (glycyl-tRNA synthetase). More specifically, the present invention relates to an antibody specifically binding to human EPRS or a fragment thereof, a production method thereof, and a pharmaceutical composition for diagnosing and treating cancer, inflammatory disease, or immunological disease, including the same. The antibody or the fragment thereof can specifically bind to the human EPRS, and does not have cross-reactivity with other proteins including the same ARS family, thereby detecting and inhibiting EPRS. Thus, the antibody or the fragment thereof can be used for detecting EPRS and also for diagnosing and treating cancer, inflammatory disease, or immunological disease associated with EPRS.
申请公布号 KR20160093502(A) 申请公布日期 2016.08.08
申请号 KR20150014616 申请日期 2015.01.29
申请人 MEDICINAL BIOCONVERGENCE RESEARCH CENTER;EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION 发明人 KIM, SUNG HOON;CHOI, YON SIK;SHIM, HYUN BO;LEE, NAM JOO
分类号 C07K16/40;A61K39/395;G01N33/573 主分类号 C07K16/40
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