发明名称 SOLID DIALYSIS A AGENT CONTAINING ALKALI METAL DIACETATE, AND TWO-PART TYPE LOW-ACETATE DIALYSIS AGENT USING SAME
摘要 [Problem] To provide a solid dialysis A agent which is to be used in preparing a bicarbonate dialysis fluid, which enables the setting of a low total acetate ion content in a dialysis fluid, and which exhibits excellent storage stability of glucose or the like and a reduced acetic acid odor.;[Solution] A solid dialysis A agent which is to be used in preparing a bicarbonate dialysis fluid, wherein: the solid dialysis A agent contains glucose, acetic acid and an acetate salt; at least a part of a mixture of the acetic acid with the acetate salt is an alkali metal diacetate; and the acetic acid/acetate salt molar ratio is adjusted to 1/0.5 to 1/2. This solid dialysis A agent makes it possible to prepare a bicarbonate dialysis fluid which has a total acetate ion concentration of 2 to less than 6 mEq/L. Further, the dialysis A agent exhibits excellent stability of ingredients and a reduced acetic acid odor.
申请公布号 US2016235785(A1) 申请公布日期 2016.08.18
申请号 US201415026798 申请日期 2014.10.02
申请人 TOMITA PHARMACEUTICAL CO., LTD. 发明人 MYOSE Michiko;NOGUCHI Hiroshi;KIKUISHI Junya;AOYAMA Hideyuki;HASHIMOTO Mina;YOSHIMOTO Yusuke
分类号 A61K33/14;A61M1/16;A61K33/00;A61K47/26;A61K47/12 主分类号 A61K33/14
代理机构 代理人
主权项 1. A solid dialysis agent A configured to be used in the preparation of a bicarbonate dialysis fluid, wherein: the solid dialysis agent A comprises glucose, acetic acid, and an acetate salt, wherein at least a part of a mixture of the acetic acid with the acetate salt is an alkali metal diacetate, wherein the molar ratio of acetic acid:acetate salt is 1:0.5 to 2, and wherein the solid dialysis agent A is to configured to be used for preparing a bicarbonate dialysis fluid having total acetate ions of 2 mEq/L or higher but less than 6 mEq/L.
地址 Tukushima JP