发明名称 (THIO) CARBAMOYL-CYCLOHEXANE DERIVATIVES AS D3/D2 RECEPTOR ANTAGONISTS
摘要 The present invention relates to new Dand Ddopamine receptor subtype preferring ligands of formula (I): wherein Rand Rrepresent independently a substituent selected from hydrogen, alkyl, aryl, cycloalkyl, aroyl, or Rand Rmay form a heterocyclic ring with the adjacent nitrogen atom; X represents an oxygen or sulphur atom; n is an integer of from 1 to 2, and/or geometric isomers and/or stereoisomers and/or diastereomers and/or salts and/or hydrates and/or solvates thereof, to the processes for producing the same, to pharmaceutical compositions containing the same and to their use in therapy and/or prevention of a condition which requires modulation of dopamine receptors.
申请公布号 EA009022(B1) 申请公布日期 2007.10.26
申请号 EA20060000364 申请日期 2004.05.21
申请人 RICHTER GEDEON VEGYSESZETI GYAR RT. 发明人 AGAINE CSONGOR EVA;GALAMBOS JANOS;NOGRADI KATALIN;VAGO ISTVAN;GYERTYAN ISTVAN;KISS BELA;LASZLOVSZKY ISTVAN;LASZY JUDIT;SAGHY KATALIN
分类号 C07D243/08;A61K31/495;A61P25/00;C07D223/04;C07D295/12;C07D295/135;C07D295/14;C07D295/215;C07D401/12 主分类号 C07D243/08
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