发明名称 |
RETROVIRAL VECTORS FOR DELIVERY OF INTERFERING RNA. |
摘要 |
<p>The present application relates to retroviral and lentiviral vectors comprising a promoter for RNA polymerase, a polylinker and a nucleic acid encoding a small hairpin RNA (shRNA) specific for a target gene. Upon introduction of said shRNA into cells, degradation of target gene messenger RNA is induced by RNA interference.</p> |
申请公布号 |
MXPA06004428(A) |
申请公布日期 |
2006.07.03 |
申请号 |
MX2006PA04428 |
申请日期 |
2004.10.21 |
申请人 |
AVENTIS PHARMACEUTICALS INC. |
发明人 |
NAYANTARA KOTHARI |
分类号 |
C12N15/11;C12N5/10;C12N15/867;(IPC1-7):C12N15/11 |
主分类号 |
C12N15/11 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|