| 发明名称 |
14-Hydroxy-6-oxamorphinans and 14-hydroxy-6-oxaisomorphinans |
| 摘要 |
14-Hydroxy-6-oxamorphinans and 14-hydroxy-6-oxaisomorphinans optionally substituted in the 3-, 7- and 17-positions have been found to possess potent analgetic, narcotic antagonist, antitussive and/or ADH inhibitory activity. The compounds are prepared by total synthesis and are not derived from opium alkaloids.
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| 申请公布号 |
US4228285(A) |
申请公布日期 |
1980.10.14 |
| 申请号 |
US19790016050 |
申请日期 |
1979.02.28 |
| 申请人 |
BRISTOL-MYERS COMPANY |
发明人 |
MONTZKA, THOMAS A.;MATISKELLA, JOHN D.;PARTYKA, RICHARD A. |
| 分类号 |
C07D221/26;C07D491/08;(IPC1-7):C07D491/18;A61K31/43 |
主分类号 |
C07D221/26 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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