摘要 |
Dihydropyridine derivatives represented by the formula (I) wherein R<1>, R<2>, and R<3> may be the same or different and each represents alkyl, cycloalkyl or alkoxyalkyl, R<4> and R<5> may be same or different and each represents hydrogen, halogen, nitro, trifluoromethyl, alkyl, cycloalkyl, alkoxy, cyano, alkoxycarbonyl or alkylthio, R<6> represents hydrogen, alkyl, cycloalkyl, aralkyl, aryl or pyridyl, X represents oxygen, sulfur, vinylene, azomethine or a group represented by <IMAGE> A represents alkylene, Ar represents aryl or pyridyl, m represents an integer of 1 to 3, and n represents an integer of 0 to 2, and their acid addition salts. These are useful as prophylactic and therapeutic agent for cardiovascular diseases. |