发明名称 DIHYDROPYRIDINE DERIVATIVES,THEIR PRODUCTION AND USE
摘要 Dihydropyridine derivatives represented by the formula (I) wherein R<1>, R<2>, and R<3> may be the same or different and each represents alkyl, cycloalkyl or alkoxyalkyl, R<4> and R<5> may be same or different and each represents hydrogen, halogen, nitro, trifluoromethyl, alkyl, cycloalkyl, alkoxy, cyano, alkoxycarbonyl or alkylthio, R<6> represents hydrogen, alkyl, cycloalkyl, aralkyl, aryl or pyridyl, X represents oxygen, sulfur, vinylene, azomethine or a group represented by <IMAGE> A represents alkylene, Ar represents aryl or pyridyl, m represents an integer of 1 to 3, and n represents an integer of 0 to 2, and their acid addition salts. These are useful as prophylactic and therapeutic agent for cardiovascular diseases.
申请公布号 ZA8302928(B) 申请公布日期 1984.06.27
申请号 ZA19830002928 申请日期 1983.04.26
申请人 TAKEDA CHEMICAL INDUSTRIES LTD 发明人 KANJI MEGURO;AKINOBU NAGAOKA
分类号 A61K;C07D;C07D211/90;C07D213/74;C07D243/08;C07D295/088;C07D401/12;C07D401/14;C07D405/04;C07D409/04;C07D413/04;C07D417/04 主分类号 A61K
代理机构 代理人
主权项
地址